| Date | Day | Time | Away Team | Home Team | Field |
| 4/17/2010 | Saturday | 11:00am | Astro's (11-12) | White Sox (11-12) | Varland - South |
| 4/17/2010 | Saturday | 4:15pm | Mets (11-12) | Dodgers (11-12) | Varland - South |
| 4/19/2010 | Monday | 7:00pm | A's (11-12) | White Sox (11-12) | Varland - South |
| 4/20/2010 | Tuesday | 7:00pm | Dodgers (11-12) | Astro's (11-12) | Varland - South |
| 4/21/2010 | Wednesday | 7:00pm | White Sox (11-12) | Mets (11-12) | Varland - South |
| 4/22/2010 | Thursday | 7:00pm | Astro's (11-12) | A's (11-12) | Varland - South |
| 4/24/2010 | Saturday | 4:15pm | Mets (11-12) | A's (11-12) | Varland - South |
| 4/26/2010 | Monday | 7:00pm | A's (11-12) | Dodgers (11-12) | Varland - South |
| 4/27/2010 | Tuesday | 7:00pm | Mets (11-12) | Astro's (11-12) | Varland - South |
| 4/28/2010 | Wednesday | 7:00pm | White Sox (11-12) | Dodgers (11-12) | Varland - South |
| 5/1/2010 | Saturday | 12:45pm | Marseilles Cardinals (11-12) | Mets (11-12) | Varland - South |
| 5/1/2010 | Saturday | 2:30pm | Marseilles Rangers (11-12) | White Sox (11-12) | Varland - South |
| 5/1/2010 | Saturday | 4:15pm | Marseilles A's (11-12) | A's (11-12) | Varland - South |
| 5/1/2010 | Saturday | 10:00am | Dodgers (11-12) | First Federal | Grand Ridge |
| 5/1/2010 | Saturday | 12:00pm | Astro's (11-12) | Durdan Electric | Grand Ridge |
| 5/3/2010 | Monday | 7:00pm | Marseilles A's (11-12) | Dodgers (11-12) | Varland - South |
| 5/3/2010 | Monday | 8:00pm | Astro's (11-12) | Marseilles Rangers (11-12) | Marseilles Park |
| 5/3/2010 | Monday | 6:00pm | A's (11-12) | First Federal | Grand Ridge |
| 5/3/2010 | Tuesday | 5:15pm | Durdan Electric | Mets (11-12) | Varland - South |
| 5/4/2010 | Tuesday | 8:00pm | White Sox (11-12) | Marseilles Cardinals (11-12) | Marseilles Park |
| 5/5/2010 | Wednesday | 8:00pm | Astro's (11-12) | Marseilles A's (11-12) | Marseilles Park |
| 5/6/2010 | Thursday | 5:15pm | Durdan Electric | A's (11-12) | Varland - South |
| 5/6/2010 | Thursday | 7:00pm | Marseilles Rangers (11-12) | Mets (11-12) | Varland - South |
| 5/7/2010 | Friday | 5:15pm | Marseilles Cardinals (11-12) | Dodgers (11-12) | Varland - South |
| 5/7/2010 | Friday | 7:00pm | First Federal | White Sox (11-12) | Varland - South |
| 5/10/2010 | Monday | 7:00pm | Durdan Electric | White Sox (11-12) | Varland - South |
| 5/10/2010 | Monday | 6:00pm | Mets (11-12) | Marseilles A's (11-12) | Marseilles Park |
| 5/11/2010 | Tuesday | 5:15pm | First Federal | Astro's (11-12) | Varland - South |
| 5/11/2010 | Tuesday | 7:00pm | Durdan Electric | Dodgers (11-12) | Varland - South |
| 5/11/2010 | Tuesday | 6:00pm | A's (11-12) | Marseilles Cardinals (11-12) | Marseilles Park |
| 5/12/2010 | Wednesday | 5:15pm | Marseilles A's (11-12) | White Sox (11-12) | Varland - South |
| 5/12/2010 | Wednesday | 7:00pm | Marseilles Rangers (11-12) | A's (11-12) | Varland - South |
| 5/12/2010 | Wednesday | 6:00pm | Mets (11-12) | First Federal | Grand Ridge |
| 5/13/2010 | Thursday | 7:00pm | Marseilles Cardinals (11-12) | Astro's (11-12) | Varland - South |
| 5/13/2010 | Thursday | 6:00pm | Dodgers (11-12) | Marseilles Rangers (11-12) | Marseilles Park |
| 5/14/2010 | Friday | 5:15pm | Mets (11-12) | Indians | North Side Big |
| 5/14/2010 | Friday | 7:00pm | Astro's (11-12) | Pirates | North Side Big |
| 5/15/2010 | Saturday | 2:30pm | Dodgers (11-12) | White Sox (11-12) | Varland - South |
| 5/18/2010 | Tuesday | 7:00pm | White Sox (11-12) | Giants | North Side Big |
| 5/19/2010 | Wednesday | 5:15pm | Orioles | Mets (11-12) | Varland - South |
| 5/19/2010 | Wednesday | 7:00pm | Angels | White Sox (11-12) | Varland - South |
| 5/19/2010 | Wednesday | 5:15pm | Astro's (11-12) | Giants | North Side Big |
| 5/19/2010 | Wednesday | 7:00pm | Cubs (9-10) | Rangers | North Side Big |
| 5/21/2010 | Friday | 7:00pm | Indians | A's (11-12) | Varland - South |
| 5/22/2010 | Saturday | 2:30pm | Orioles | A's (11-12) | Varland - South |
| 5/22/2010 | Saturday | 9:00am | Dodgers (11-12) | Rockies | North Side Big |
| 5/22/2010 | Saturday | 12:30pm | Mets (11-12) | Pirates | North Side Big |
| 5/21/2010 | Friday | 5:15 pm | Dodgers (11-12) | Giants | North Side Big |
| 5/24/2010 | Monday | 7:00pm | Angels | Mets (11-12) | Varland - South |
| 5/24/2010 | Monday | 7:00pm | White Sox (11-12) | Orioles | North Side Big |
| 5/25/2010 | Tuesday | 5:15pm | Pirates | A's (11-12) | Varland - South |
| 5/25/2010 | Tuesday | 7:00pm | Rockies | Astro's (11-12) | Varland - South |
| 5/26/2010 | Wednesday | 7:00pm | Indians | Dodgers (11-12) | Varland - South |
| 5/26/2010 | Wednesday | 7:00pm | Astro's (11-12) | Angels | North Side Big |
| 5/27/2010 | Thursday | 5:15pm | Giants | A's (11-12) | Varland - South |
| 5/27/2010 | Thursday | 7:00pm | Rockies | White Sox (11-12) | Varland - South |
| 5/28/2010 | Friday | 7:00pm | Pirates | Dodgers (11-12) | Varland - South |
| 5/28/2010 | Friday | 7:00pm | A's (11-12) | Angels | North Side Big |
| 5/29/2010 | Saturday | 12:45pm | Orioles | Astro's (11-12) | Varland - South |
| 5/29/2010 | Saturday | 2:30pm | Angels | Dodgers (11-12) | Varland - South |
| 5/29/2010 | Saturday | 9:00am | White Sox (11-12) | Indians | North Side Big |
| 5/29/2010 | Saturday | 10:45am | Mets (11-12) | Giants | North Side Big |
| 5/31/2010 | Monday | 5:15pm | Pirates | White Sox (11-12) | Varland - South |
| 5/31/2010 | Monday | 7:00pm | Rockies | A's (11-12) | Varland - South |
| 6/1/2010 | Tuesday | 5:15pm | Orioles | Dodgers (11-12) | Varland - South |
| 6/1/2010 | Tuesday | 5:15pm | Mets (11-12) | Rockies | North Side Big |
| 6/1/2010 | Tuesday | 7:00pm | Astro's (11-12) | Indians | North Side Big |
| 6/2/2010 | Wednesday | 7:00pm | White Sox (11-12) | A's (11-12) | Varland - South |
| 6/4/2010 | Friday | 5:15pm | Astro's (11-12) | Dodgers (11-12) | Varland - South |
| 6/4/2010 | Friday | 7:00pm | A's (11-12) | Mets (11-12) | Varland - South |
| 6/14/2010 | Monday | 5:15pm | White Sox (11-12) | Astro's (11-12) | Varland - South |
| 6/14/2010 | Monday | 7:00pm | Dodgers (11-12) | Mets (11-12) | Varland - South |
| 6/15/2010 | Tuesday | 7:00pm | Dodgers (11-12) | A's (11-12) | Varland - South |
| 6/16/2010 | Wednesday | 7:00pm | A's (11-12) | Astro's (11-12) | Varland - South |
| 6/17/2010 | Thursday | 7:00pm | Mets (11-12) | White Sox (11-12) | Varland - South |
| 6/18/2010 | Friday | 7:00pm | Astro's (11-12) | Mets (11-12) | Varland - South |